Kyle Shanahan told NBC Sports Bay Area’s Greg Papa on “49ers Game Plan" that rookie running back Isaac Guerendo could be set ...

Fortunately, the 49ers have landed the ideal Week 3 foe to help make things right in the Los Angeles Rams, who are somehow ...

Injuries are piling up for the 49ers as they gear up for a critical showdown against the Rams. Head coach Kyle Shanahan ...

The recent retirement of Aaron Donald, the three-time Defensive Player of the Year and a key figure in the Rams' defense, has ...

Suddenly in doubt for the Week 3 game at L.A. are tight end George Kittle, defensive end Nick Bosa, and cornerback Charvarius ...

In an interview on "The Insiders", Pittsburgh Steelers linebacker Alex Highsmith talks about his team's defensive identity ...

Charles Robinson & Frank Schwab react to the New York Jets dominant victory over the New England Patriots on Thursday Night ...

New England Patriots head coach Jerod Mayo explains that Patriots quarterback Jacoby Brissett "is our quarterback until I say ...

Check out some of S Talanoa Hufanga's must-visit spots around Los Angeles, California ahead of the 49ers vs. Rams Week ...

San Francisco 49ers' George Kittle is listed as doubtful for Sunday's game against the Rams. He joins Christian McCaffrey and ...

San Francisco 49ers head coach Kyle Shanahan spoke with reporters after Friday's practice as the team prepares for its Week 3 matchup against the Los ...

SANTA CLARA, Calif. (AP) — The San Francisco 49ers will likely be without All-Pro tight end George Kittle for Sunday's game ...